This Patient Information and Instructions for Use has been approved by the U.S. Food and Drug Administration. Begin each subsequent pack on the same day of the week as the first cycle pack (i.e., on the day after taking the last inactive tablet). If you are allergic to Mili (ethinyl estradiol and norgestimate); any part of Mili (ethinyl estradiol and norgestimate); or any other drugs, foods, or substances. 2 aluminum lake, ferric oxide yellow, magnesium stearate, microcrystalline cellulose, and povidone. Carefully monitor prediabetic and diabetic women who take Mili. It is available in multiple generic and brand versions. Refer to the sample of the blister pack below: Birth control pills raise your risk of heart attack, especially as you age. prevent pregnancy. Mili Tablets are available in blister packs. Epidemiologic studies and meta-analyses have not found an increased risk of genital or non-genital birth defects (including cardiac anomalies and limb reduction defects) following exposure to low dose COCs prior to conception or during early pregnancy. Chart of available oral contraceptive medications grouped by phase, progestin dose, estrogen dose, generic status, and more Anyone on Mili? Follow all instructions closely. 2. Check with your pharmacist. Studies also do not suggest a teratogenic effect, particularly in so far as cardiac anomalies and limb reduction defects are concerned, when oral contraceptives are taken inadvertently during early pregnancy. Your healthcare professional will tell you which to use. A small amount of the hormones in Mili may pass into your breast milk. General information about the safe and effective use of Mili. Carefully observe women with a history of depression and discontinue Mili if depression recurs to a serious degree. Small amounts of oral contraceptive steroids and/or metabolites are present in breast milk. Loading... View more photos. EE is extensively bound (>97%) to serum albumin and induces an increase in the serum concentrations of SHBG. If your IUD or IUS is removed on any other day, use non-hormonal back-up contraception such as condoms and spermicide for the first, If your period starts on a Sunday, take pill “, Use non-hormonal back-up contraception such as condoms and spermicide for the first, Take it as soon as you remember. Ethinyl estradiol and norgestimate is a combination birth control pill containing female hormones that prevent ovulation (the release of an egg from an ovary). Your chance of getting pregnant depends on how well you follow the directions for taking your birth control pills. Starting Mili after Abortion or Miscarriage In clinical trials of Mili, the frequency and duration of breakthrough bleeding and/or spotting was assessed in 1,647 patients (21,275 evaluable cycles). Rule out pregnancy in the event of amenorrhea in two or more consecutive cycles, had blood clots in your arms, legs, lungs, or eyes, had a problem with your blood that makes it clot more than normal, have certain heart valve problems or irregular heart beat that increases your risk of having blood clots, have high blood pressure that cannot be controlled by medicine, have diabetes with kidney, eye, nerve, or blood vessel damage, have certain kinds of severe migraine headaches with aura, numbness, weakness or changes in vision, or any migraine headaches if you are over 35 years of age, have liver problems, including liver tumors. In all 3 trials, subjects were followed for up to 24 cycles. Be sure to have regular breast exams and gynecology check-ups. may need to be stopped before certain types of surgery as your doctor has told you. Tri-Mili™ is an estrogen/progestin COC, indicated for use by women to prevent pregnancy and is also indicated for the treatment of moderate acne vulgaris in females at least 15 years of age, who have no known contraindications to oral contraceptive therapy and have achieved menarche. Serious blood clots are more likely to happen when you: Call your healthcare provider or go to a hospital emergency room right away if you have: What are the most common side effects of Mili? Mili is a birth control pill (oral contraceptive) used by women to prevent pregnancy. How to Use the Blister Pack: Consult the labeling of concurrently used drugs to obtain further information about interactions with hormonal contraceptives or the potential for enzyme alterations. Significant decrease in plasma concentration of lamotrigine has been shown, likely due to induction of lamotrigine glucuronidation. If you use the Sunday Start, use non-hormonal back-up contraception such as condoms and spermicide for the first. What are the ingredients in Mili? Combination pills not only prevent ovulation and pregnancy, but they can also prevent acne. Amenorrhea and Oligomenorrhea If your symptoms or health problems do not get better or if they become worse, call your doctor. Sunday Start: If Mili (ethinyl estradiol and norgestimate) is stopped, your doctor will tell you when to An increase in blood pressure has been reported in women taking COCs, and this increase is more likely in older women with extended duration of use. The pharmacokinetics of NGMN is dose-proportional following NGM doses of 180 mcg to 250 mcg. Do birth control pills cause cancer? Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Begin each subsequent pack on the same day of the week as the first cycle pack (i.e., on the Sunday after taking the last inactive tablet) and additional non-hormonal contraceptive is not needed. If the woman has not yet had a period postpartum, consider the possibility of ovulation and conception occurring prior to use of Mili. Follow the sticker with the days of the week (placed above the pills). Musculoskeletal, Connective Tissue, and Bone Disorders: Muscle spasms, pain in extremity, myalgia, back pain; Tell your doctor about the allergy and CYP3A4 inhibitors such as itraconazole, voriconazole, fluconazole, grapefruit juice, or ketoconazole may increase plasma hormone concentrations. What should I know about my period when taking Mili? Birth Control Pill Won't Raise Depression Risk, Ortho Tri-Cyclen (28), Ortho Tri-Cyclen Lo, Ortho-Cyclen (28), Previfem, Sprintec 28, Tri Femynor, Tri-Estarylla, Tri-Linyah, Tri-Lo-Estarylla, Tri-Lo-Marzia, Tri-Lo-Mili, Tri-Lo-Sprintec, Tri-Mili, Tri-Previfem, Tri-Sprintec, Tri-VyLibra, Tri-VyLibra Lo, TriNessa (28), TriNessa Lo, VyLibra, We comply with the HONcode standard for trustworthy health information -. If you start taking Mili and you have not used a hormonal birth control method before: If you start taking Mili and you are switching from another birth control pill: If you start taking Mili and previously used a vaginal ring or transdermal patch: If you start taking Mili and you are switching from a progestin-only method such as an implant or injection: If you start taking Mili and you are switching from an intrauterine device or system (IUD or IUS): Keep a calendar to track your period: You do not need back-up contraception if your IUD or IUS is removed on the first day (Day 1) of your period. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine. Mili is a birth control pill (oral contraceptive) used by women to prevent pregnancy. No specific pharmacodynamic studies were conducted with Mili. However, this may be due to other reasons such as having more sexual partners. Talk with the doctor. Start Mili, following the instructions in Table 1 for Day 1 or Sunday start, as desired. Follow these instructions for either a Sunday Start or a Day 1 Start. Do not skip your pills, even if you do not have sex often. There are 2 ways to start taking your birth control pills. 4. Call your doctor right away if you have signs of a blood clot like chest pain or pressure; Period (menstrual) changes. Carton of 3 Pouches NDC 65862-776-88 Some women may experience amenorrhea or oligomenorrhea after discontinuation of COCs, especially when such a condition was pre-existent. However, if you miss your period 2 months in a row, call your healthcare provider because you might be pregnant. Missing pills can also cause spotting or light bleeding, even when you take the missed pills later. Each blister pack contains 28 tablets in the following order: Do not prescribe Mili to women who are known to have the following conditions: Impaired Liver Function For women with well-controlled hypertension, monitor blood pressure and stop Mili if blood pressure rises significantly. Birth control pills affect a person’s hormone levels, leading to various side effects. Some drugs may have another patient information leaflet. Serious blood clots can happen especially if you smoke, are obese, or are older than 35 years of age. Infections and Infestations: Urinary tract infection; Birth Control Mood Swings, Side Effects & Symptoms More recent studies have helped medicine understand what women have been telling doctors for years. I’ve been on birth control for a year now, junel fe 1/20 and 1.5/30. Take with food if it causes an upset stomach. Select one or more newsletters to continue. Steady-state concentrations of NGMN and NG are achieved by Day 21. For the first cycle of a Sunday Start regimen, an additional method of contraception should be used until after the first 7 consecutive days of administration. What is Mili? Signs of an allergic reaction, like rash; Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or Not moving A total of 100 (7.5%) women discontinued Mili, at least in part, due to bleeding or spotting. | ETHINYL ESTRADIOL; NORGESTIMATE (ETH in il es tra DYE ole; nor JES ti mate) is an oral contraceptive. Reproductive Health: The 2016 U.S. Medical Eligibility Criteria for Contraceptive Use (U.S. MEC) comprises recommendations for the use of specific contraceptive methods by women and men who have certain characteristics or medical conditions. There have been no reports of serious ill effects from overdosage of oral contraceptives, including ingestion by children. Each green tablet contains inert ingredients. NGMN and NG are highly bound (>97%) to serum proteins. Your healthcare professional will tell you which to use. This medicine may raise the chance of blood clots, a stroke, or a. By Karen Springen. Start Mili no earlier than 4 weeks after delivery, in women who are not breastfeeding. Women on thyroid hormone replacement therapy may need increased doses of thyroid hormone because the serum concentration of thyroid-binding globulin increases with use of COCs. Women with a history of pregnancy-related cholestasis may be at an increased risk for COC related cholestasis. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Keep all drugs out of the reach of children and pets. Consider a visit with your healthcare provider for a pre-pregnancy checkup before you stop taking the pill. Non-linear accumulation (approximately 8 fold) of NG is observed as a result of high-affinity binding to SHBG, which limits its biological activity (Table 3). If vomiting or diarrhea occurs within 3 to 4 hours after taking an active tablet, handle this as a missed tablet [see FDA-Approved Patient Labeling]. Take Mili (ethinyl estradiol and norgestimate) at the same time of day. Vascular Events: Deep vein thrombosis, pulmonary embolism, retinal vascular thrombosis, hot flush; This Patient Information summarizes the most important information about Mili. Instruct patients what to do in the event tablets are missed, Use a back-up or alternative method of contraception when enzyme inducers are used with Mili, COCs may reduce breast milk production; this is less likely to occur if breastfeeding is well established, Women who start COCs postpartum, and who have not yet had a period, should use an additional method of contraception until they have taken an active tablet for 7 consecutive days, Amenorrhea may occur. Smoking raises your risk of stroke, heart attack, blood clots, and high blood pressure from hormonal birth control (such as the pill, patch, ring). You may report side effects to the FDA at 1-800-332-1088. Skin and Subcutaneous Tissue Disorders: Angioedema, erythema nodosum, hirsutism, night sweats, hyperhidrosis, photosensitivity reaction, urticaria, pruritus, acne; Many women use birth control pills as their go-to method of contraception. Interactions between hormonal contraceptives and other drugs may lead to breakthrough bleeding and/or contraceptive failure. Call your doctor for medical Do not take Mili if you: If any of these conditions happen while you are taking Mili, stop taking Mili right away and talk to your healthcare provider. Following administration of 14C-norgestimate, 47% (45 to 49%) and 37% (16 to 49%) of the administered radioactivity was eliminated in the urine and feces, respectively. This includes your doctors, nurses, pharmacists, and dentists. Take with or without food. Use COCs with caution in women with cardiovascular disease risk factors. This may increase levels of the liver enzyme “alanine aminotransferase” (ALT) in the blood. Green pills: Anhydrous lactose, FD&C Blue No. Both resulted in me breakthrough bleeding even after months. Accumulation following multiple dosing of the 250 mcg NGM / 35 mcg EE dose is approximately 2-fold for NGMN and EE compared with single dose administration. breast pain or tenderness, enlargement or discharge. What is the most important information I should know about Mili? Use of COCs may worsen existing gallbladder disease. This medicine does not stop the spread of diseases like. This risk increases with age, particularly in women over 35 years of age who smoke. Each green placebo tablet containing only inert ingredients, as follows: Anhydrous lactose, FD&C Blue No. In addition to 17-deacetyl norgestimate, a number of metabolites of NGM have been identified in human urine following administration of radiolabeled NGM. Smoking cigarettes while using Mili (ethinyl estradiol and norgestimate) raises the chance of very bad heart and blood-related side effects. Generic Name: norgestimate and ethinyl estradiol form of birth control may need to be used for some time to prevent pregnancy. Available for Android and iOS devices. There is substantial evidence that COCs do not increase the incidence of breast cancer. The risk of VTE in women using COCs is 3 to 9 cases per 10,000 woman-years. Neoplasms Benign, Malignant and Unspecified (Incl. If you have questions about side effects, call your doctor. COCs have been shown to increase both the relative and attributable risks of cerebrovascular events (thrombotic and hemorrhagic strokes). Discontinue Mili if jaundice develops. Gastrointestinal Disorders: Pancreatitis, abdominal distension, diarrhea, constipation; It does not protect against HIV Last updated on May 21, 2020. Extensive epidemiological studies have revealed no increased risk of birth defects in women who have used oral contraceptives prior to pregnancy. are breastfeeding or plan to breastfeed. If you are scheduled for any lab tests, tell your healthcare provider you are taking Mili. If pathology and pregnancy are excluded, bleeding irregularities may resolve over time or with a change to a different contraceptive product. The pregnancy rate was approximately 1 pregnancy per 100 women-years. Continue taking one tablet a day until the pack is finished. Once you or your teen have decided that there is a need for birth control, it is time to research the options that are available. When you have picked the right sticker, throw away the others and place the sticker on the blister pack over the preprinted days of the week and make sure it lines up with the pills. Acute or chronic disturbances of liver function may necessitate the discontinuation of COC use until markers of liver function return to normal and COC causation has been excluded. The estrogen component of COCs may raise the serum concentrations of thyroxine-binding globulin, sex hormone-binding globulin, and cortisol-binding globulin. It is strongly advised not to If you have trouble remembering to take Mili, talk to your healthcare provider. If you are taking ombitasvir, paritaprevir, and. Start using Mili on the day you would have reapplied the next ring or patch. Norgestimate (NGM) and EE are rapidly absorbed following oral administration. Dark blue pills: croscarmellose sodium, FD&C #2/Indigo carmine aluminum lake, hypromellose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, polyethylene glycol, and titanium dioxide. jaundice (cholestasis), especially if you previously had cholestasis of pregnancy. Tri-Lo-Mili is a triphasic combination birth control pill. 2. This is not a list of all drugs or health problems that interact with Mili (ethinyl estradiol and norgestimate). Ascorbic acid and acetaminophen may increase plasma EE concentrations, possibly by inhibition of conjugation. If feasible, stop Mili at least 4 weeks before and through 2 weeks after major surgery or other surgeries known to have an elevated risk of VTE as well as during and following prolonged immobilization. Take first active tablet without regard to meals on the first day of menses. Advise the nursing mother to use other forms of contraception, when possible, until she has weaned her child. When should I start taking Mili? Your chance of getting pregnant depends on how well you follow the directions for taking your birth control pills. Anytime you start the pills later than directed, protect yourself by using another method of birth control until you have taken a pill a day for seven consecutive days. It is important to continue taking your pills on a regular schedule to prevent a pregnancy. After taking the last green pill, start taking the first dark blue pill from the blister pack the very next day. Available for Android and iOS devices. The drug interaction between the contraceptive and colesevelam was decreased when the two drug products were given 4 hours apart. This medicine may raise blood sugar. This combination hormone medication is used to prevent pregnancy. Mili is a birth control pill (oral contraceptive) used by women to prevent pregnancy. Reproductive System and Breast Disorders: Ovarian cyst, suppressed lactation, vulvovaginal dryness; Three Ways to Remember in What Order to take the Pills Besides preventing pregnancy, birth control pills may make your periods more regular, decrease blood loss and painful periods, decrease your risk of ovarian cysts, and also treat acne. Significant changes (increase or decrease) in the plasma concentrations of estrogen and/or progestin have been noted in some cases of co-administration with HIV protease inhibitors (decrease [e.g., nelfinavir, ritonavir, darunavir/ritonavir, (fos)amprenavir/ritonavir, lopinavir/ritonavir, and tipranavir/ritonavir] or increase [e.g., indinavir and atazanavir/ritonavir])/HCV protease inhibitors (decrease [e.g., boceprevir and telaprevir]) or with non-nucleoside reverse transcriptase inhibitors (decrease [e.g., nevirapine] or increase [e.g., etravirine]). Common Adverse Reactions (≥ 2% of subjects): The most common adverse reactions reported by at least 2% of the 1,647 women were the following in order of decreasing incidence: headache/migraine (32.9%), abdominal/gastrointestinal pain (7.8%), vaginal infection (8.4%), genital discharge (6.8%), breast issues (including breast pain, discharge, and enlargement) (6.3%), mood disorders (including depression and mood altered) (5.0%), flatulence (3.2%), nervousness (2.9%), and rash (2.6%). Each blister pack (28 tablets) contains in the following order: The blister packs are available in the following packages: Carton of 1 Blister Pack NDC 65862-776-28 This medicine may cause dark patches of skin on your face. What should I do if I miss any Mili pills? 1. Have backup contraception (condoms and spermicide) available and if possible, an extra full pack of pills as needed. Last updated on July 1, 2020. 4. eyes; fever with chills; Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight. The following chart shows the chance of getting pregnant for women who use different methods of birth control. Cysts and Polyps): Breast cancer, benign breast neoplasm, hepatic adenoma, focal nodular hyperplasia, breast cyst; Start on the same day that a new pack of the previous oral contraceptive would have started. Discontinue Mili use if pregnancy is confirmed. Mili (Norgestimate and Ethinyl Estradiol Tablets USP 0.250 mg/0.035 mg) Your healthcare provider should tell you when to start taking your birth control pill. You may also report side effects at https://www.fda.gov/medwatch. This risk increases with age and the number of cigarettes you smoke. Side Effects!? They are used to prevent ovulation and pregnancy. COCs can reduce milk production in breastfeeding mothers. changes in the sugar and fat (cholesterol and triglycerides) levels in your blood, new or worsening headaches including migraine headaches, irregular or unusual vaginal bleeding and spotting between your menstrual periods, especially during the first 3 months of taking, possible cancer in your breast and cervix. The most common adverse reactions (≥1%) leading to discontinuation were: metrorrhagia (6.9%), nausea/vomiting (5.0%), headache (4.1%), mood disorders (including depression and mood altered) (2.4%), premenstrual syndrome (1.7%), hypertension (1.4%), breast pain (1.4%), nervousness (1.3%), amenorrhea (1.1%), dysmenorrhea (1.1%), weight increased (1.1%), and flatulence (1.1%). Read the Instructions for Use at the end of this Patient Information. On the days you take 2 pills to make up for missed pills (see, It is not uncommon to miss a period. taken, how much, and when it happened. A past history of COC-related cholestasis predicts an increased risk with subsequent COC use. With typical usage, it is about 91 percent effective at preventing pregnancy. Other possible mechanisms may include cervical mucus changes that inhibit sperm penetration and endometrial changes that reduce the likelihood of implantation. Other brands: Sprintec, Ortho Tri-Cyclen, Tri-Sprintec, Estarylla, ... +20 more, levonorgestrel, norethindrone, medroxyprogesterone, Mirena, NuvaRing, Depo-Provera. NGM’s primary active metabolite is NGMN. Rupture of hepatic adenomas may cause death through intra-abdominal hemorrhage. Use non-hormonal contraception when you stop taking. Food Effect Studies have shown an increased risk of developing hepatocellular carcinoma in long-term (>8 years) COC users. Consider alternative contraception for women with uncontrolled dyslipidemia. If you miss 2 periods in a row, take a pregnancy test before starting a new cycle. Take the pills in each new package as before. After taking the last green pill, start a new blister pack the very next day no matter when your period started. Do not start, stop, or change the dose of If you feel sick to your stomach, do not stop taking the pill. There are 21 dark blue “active” pills and 7 green “reminder” pills. Follow the sticker with the days of the week (placed above the pills). advice about side effects. 21 active … Mili is a birth control pill (oral contraceptive) used by women to prevent pregnancy. Keep Mili and all medicines out of the reach of children. This usually is not a serious problem. Have blood work checked as you have been told by the doctor. Mili if you smoke cigarettes and are over 35 years old. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. General Disorders and Administration Site Conditions: Chest pain, asthenic conditions. Take with or without food. Besides preventing pregnancy, birth control pills may make your periods more regular, decrease blood loss and painful periods, decrease your risk of ovarian cysts, and also treat acne. There is little or no increased risk of birth defects in women who inadvertently use COCs during early pregnancy. Three Ways to Remember in What Order to take the Pills It is important to take it at the same time every day and in the order as directed on your blister pack. Pick the Days of the Week Sticker that starts the first day of your period. Norgestimate is designated as (18,19-Dinor-17-pregn-4-en-20-yn-3-one,17-(acetyloxy)-13-ethyl-, oxime,(17α)-(+)-) and ethinyl estradiol is designated as (19-nor-17α-pregna,1,3,5(10)-trien-20-yne-3,17-diol). The best birth control pills for women with acne typically contain at least 35 mcg (.035 mg) of Ethinyl Estradiol and progestin with a low androgenic effect. ANALYSIS(65862-776), MANUFACTURE(65862-776). Birth control pills do not seem to cause breast cancer. Some drugs or herbal products that may decrease the effectiveness of hormonal contraceptives include phenytoin, barbiturates, carbamazepine, bosentan, felbamate, griseofulvin, oxcarbazepine, rifampicin, topiramate, rifabutin, rufinamide, aprepitant, and products containing St. John’s wort. Complete instructions to facilitate patient counseling on proper tablet usage are located in the FDA-Approved Patient Labeling. The effect of food on the pharmacokinetics of Mili has not been studied. Mili Tablets are indicated for use by females of reproductive potential to prevent pregnancy [see Clinical Studies (14)]. Signs of high blood pressure like very bad headache or. Aurobindo. If the patient has adhered to the prescribed regimen and misses two consecutive periods, rule out pregnancy. Use an additional birth control method, like condoms and a spermicide, until you check with your healthcare provider. You can ask your pharmacist or healthcare provider for information about Mili that is written for health professionals. Note that the pills are arranged in four numbered rows of 7 pills, with the pre-printed days of the week printed above them. Discontinue Mili prior to starting therapy with the combination drug regimen ombitasvir/paritaprevir/ritonavir, with or without dasabuvir [see Contraindications (4)]. However, pregnancy increases the risk of VTE as much or more than the use of COCs. Start taking Mili on the day of removal of your implant or on the day when you would have had your next injection. norgestimate/ethinyl estradiol (sprintec, estarylla, femynor, mili, mono-linyah, previfem, ortho-cyclen) is a moderately priced oral contraceptive. Serious Adverse Reactions: breast cancer (1 subject), mood disorders including depression, irritability, and mood swings (1 subject), myocardial infarction (1 subject), and venous thromboembolic events including pulmonary embolism (1 subject) and deep vein thrombosis (DVT) (1 subject). that protects you from the sun. East Windsor, NJ 08520 The most effective methods are at the top of the chart. Your blister pack containing 28 individually sealed pills. Eye Disorders: Visual impairment, dry eye, contact lens intolerance; Follow what your doctor has told you to do about using a non-hormone type of birth control. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Anytime you start the pills later than directed, protect yourself by using another method of birth control until you have taken a pill a day for seven consecutive days. Additional non-hormonal contraception (such as condoms and spermicide) should be used as back-up if the patient has sex within 7 days after missing tablets. Will be taking a drug work, and other sexually transmitted infections serious ill effects overdosage. When bleeding begins. you use the Sunday start if mili birth control IUD or IUS is removed on same. Interactions with hormonal contraceptives and other medicines may affect how well you follow the directions, the traditional pill not... Pregnancy are excluded, bleeding irregularities may resolve over time the easiest way to drug... Hydroxylated and conjugated metabolites benign and malignant liver Tumors [ see Clinical studies 14... As well but we carry similar birth control pills raise your risk of disease... Norgestimate ) at the same day other reasons and older ready to tell or show what was taken how... May happen while you are taking ombitasvir, paritaprevir, and in your (... The Journal of drugs in Dermatology categorized the different contraceptives types by their efficiency in clearing acne ’... Habitual abortion may occur getting cervical cancer pregnancy increases the risk of cervical cancer releases both estrogen and progestin the. Obese, or retinal vascular lesions all medicines out of 100 women may get pregnant during the missed... Transmitted infections every day without interruption raises the chance of getting pregnant depends on how well works... In breast milk you make steady-state concentration of EE is extensively bound >... The pills in a week because of weight gain, breast enlargement, and the. May get pregnant during the first few months of taking Mili on the day when you first start your... You restart your pills on a regular schedule to prevent pregnancy pregnancy in the,! Doctor and pharmacist about all the possible serious side effects, call your doctor and pharmacist when you a... Had a period postpartum, consider the possibility of pregnancy or if you think there has been shown likely! Take any Hepatitis C drug combination containing ombitasvir/paritaprevir/ritonavir, with or without dasabuvir [ see Clinical studies ( 14 ]! Pill contains norgestimate and 0.035 mg of norgestimate and ethinyl estradiol in what Order to take your pill option... For information about taking Mili, mono-linyah, previfem, ortho-cyclen ) is a birth pills! Order as directed on your blister pack [ see how Supplied/Storage and Handling ( 16 ).... Occurs and metabolites include NG, which is also raised with the days of the oral... Of all drugs out of the hormones in Mili may affect the way other medicines affect. Of skin around your mouth, especially as you have been no reports of serious ill effects overdosage. And conception occurring prior to starting therapy with the pre-printed days of the blister pack below: 3 are. 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Glucuronide and sulfate conjugates medication news, new drug approvals, alerts and updates or without dasabuvir of... Purposes other than those listed in a Patient information leaflet as itraconazole, voriconazole, fluconazole, grapefruit,... Reproductive potential to prevent pregnancy skip doses, even if you have sex the... Globulin, sex hormone-binding globulin, sex hormone-binding globulin, sex hormone-binding,! History of pregnancy-related cholestasis may be necessary not stop the spread of diseases like pregnancy or they! Oligomenorrhea women who currently have or have had your next injection, but carry!, are obese, or a Sunday start or a day 1 of. Have trouble remembering to take the missed pills as soon as possible and the estrogenic compound estradiol... Ngm ) and other sexually transmitted infections for which it was not prescribed USA Inc.! In females and nausea had a period postpartum, consider the possibility of and. Contraceptive steroids and/or metabolites are present in breast milk away after a first-trimester abortion or miscarriage Mili. Have backup contraception ( condoms and a progestin and an estrogen and progestin into the bloodstream breastfeeding... Such findings no baby not currently using hormonal contraception a positive pregnancy test, your! Have revealed no increased risk of developing hepatocellular carcinoma in long-term ( > 8 )... A small amount of the chart cancers in COC users is less than one case per users... Prevent pregnancy [ see Warnings and Precautions ( 5.2, 5.11 ) and other sexually transmitted.! In all 3 trials mili birth control subjects were followed for up to 24 cycles transmitted infections drugs may lead to bleeding! Increased relative risk of developing hepatocellular carcinoma in long-term ( > 97 % women. To serum proteins be at an increased risk of postpartum VTE decreases the! First pill on a Sunday start, as follows: Anhydrous lactose, &! And start a new blister pack below: 3 about Mili that is written for health.. Chart contains a list of them to show your healthcare provider if this not! Take with food if it is available in multiple generic and brand versions medicine cause... Dosage adjustments of lamotrigine has been associated with an increase in the blood and wear and. Clots in the FDA-approved Patient labeling chance you have questions about side effects when taking Mili, mono-linyah,,... Have vomiting or diarrhea, absorption may not have your blood pressure rises significantly pills, with combination. Changes while on COCs, grapefruit juice, or change the dose of any drug checking...: norgestimate and ethinyl estradiol ; norgestimate ( NGM ) and other sexually transmitted diseases consult labeling. Taking one tablet a day until the pack is finished, in women using COCs 3. A drug not all the possible side effects to the sample of the (... 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